Regioselectivity in the Addition of Grignard Reagents to Bis(2-benzothiazolyl) Ketone: C- vs. O-Alkylation Using Aryl Grignard Reagents

ChemInform Abstract: Unexpected Regiosel

ChemInform Abstract: Unexpected Regioselectivity in the Attack of Vinyl Grignard Reagents to Bis(2-benzothiazolyl) Ketone.

✍ C. BOGA; L. FORLANI; P. E. TODESCO 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 30 KB 👁 1 views

Unexpected Regioselectivity in the Attack of Vinyl Grignard Reagents to Bis(2-benzothiazolyl) Ketone. -Surprisingly, the reaction of ketone (I) with vinylmagnesium bromide ( IIa) does not give the expected carbinol (IVa) by normal 1,2-carbonyl addition but the vinyl ether (IIIa) is obtained exclusiv