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Regioselectivity in SNH reactions of some 3-nitro-1,8-naphthyridines with chloromethyl phenyl sulfone

✍ Scribed by Maria Grzegozek; Marian Woźniak; Andrzej Barański; Henk C. Van Der Plas


Book ID
112130054
Publisher
Journal of Heterocyclic Chemistry
Year
1991
Tongue
English
Weight
209 KB
Volume
28
Category
Article
ISSN
0022-152X

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Regioselectivity in SNH Reactions of Nit
✍ Grzegożek, Maria ;Woźniak, Marian ;van der Plas, Henk C. 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 333 KB

## Abstract 3‐Nitro‐, 4‐nitro‐, 7‐nitro‐, 5,7‐dinitro‐, and 6,8‐dinitroquinoline react with the carbanion of chloromethyl phenyl sulfone to give products of substitution of hydrogen at positions 4, 3, 8, 6,8, and 5,7, respectively. The reactions are found by quantum chemical calculations to be cont