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Regioselective three-component synthesis of novel indeno[1,2-b]-pyrazolo[4,3-e]pyridines-fused derivatives of 4-azafluorenone alkaloid

✍ Scribed by Jairo Quiroga; Débora Cobo; Braulio Insuasty; Rodrigo Abonía; Silvia Cruz; Manuel Nogueras; Justo Cobo


Book ID
102340266
Publisher
Journal of Heterocyclic Chemistry
Year
2008
Tongue
English
Weight
335 KB
Volume
45
Category
Article
ISSN
0022-152X

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✦ Synopsis


Abstract

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New fused indeno[1,2‐b]pyridine derivatives have been prepared in a multicomponent reaction from benzaldehydes, indanedione and the appropriate aminoheteroaryl compound. The simple methodology permitted the syntheses of a series of indeno[1,2‐b]pyrazolo[4,3‐e]pyridines 4 from 5‐aminopyrazol 1 and modulated by the corresponding benzaldehyde 2.


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An efficient and clean synthesis of inde
✍ Shuliang Wang; Ning Ma; Ge Zhang; Feng Shi; Bo Jiang; Han Lu; Yuan Gao; Shujiang 📂 Article 📅 2010 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 118 KB

## Abstract magnified image A series of new indeno[1,2‐__b__]pyrazolo[4,3‐__e__]pyridin‐5(1__H__)‐one derivatives were synthesized by three‐component reactions of 1,3‐indandione, 3‐methyl‐1__H__‐pyrazol‐5‐amine, and aldehyde in water under microwave irradiation without any catalyst. J. Heterocyclic