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Regioselective synthesis of polysubstituted 4H-thiopyrans from β-oxodithioesters

✍ Scribed by Madabhushi, Sridhar; Kurva, Srinivas; Vangipuram, Venkata Sairam; Sriramoju, Vinodkumar; Mallu, Kishore Kumar Reddy; Nanubolu, Jagadeesh Babu


Book ID
125795277
Publisher
Elsevier Science
Year
2014
Tongue
French
Weight
702 KB
Volume
55
Category
Article
ISSN
0040-4039

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A new regioselective synthesis for aminonitrones of type 4 via oxidative modification of 4H-imidazoles 1 has been developed. An X-ray structural analysis revealed an unexpected tautomeric fixation of the hydrogen atom in 4. NMR investigations of the 15 N-labelled derivative 4b showed that this fixat