Regioselective synthesis of polyfluoroalkyl-substituted 7-(1H-1,2,3-triazol-1-yl)-6,7-dihydro-1H-indazol-4(5H)-ones
✍ Scribed by T. S. Khlebnikova; Yu. A. Piven’; A. V. Baranovskii; F. A. Lakhvich
- Book ID
- 114993882
- Publisher
- SP MAIK Nauka/Interperiodica
- Year
- 2012
- Tongue
- English
- Weight
- 257 KB
- Volume
- 48
- Category
- Article
- ISSN
- 1070-4280
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## Abstract magnified image A regiospecific approach to each __N__‐methyl‐5‐(1__H__‐indol‐2‐yl)‐6,7‐dihydro‐2__H__‐indazole isomer is reported. The 1‐methyl isomer **1** was prepared from 5‐bromo‐1‐methyl‐6,7‐dihydro‐1__H__‐indazole **3** and indole‐2‐boronate **5** by palladium catalyzed Suzuki c
## Abstract The aza‐Wittig reactions of benzaldehyde‐, acetophenone‐ and benzophenone 1‐[(triphenylphosphor‐anylidene)amino]ethylidenehydrazones (**1**) with 2,3‐furandiones **6** provide a new route to 4__H__,8__H__‐1,2,4‐triazolo[1,5‐__c__][1,3]oxazepin‐4‐ones **14** or 5,6‐dihydro‐7__H__,12__H__
## Abstract Vilsmeier formylation of the 4‐amino‐2‐pyridinones 4a–d leads to the formation of the corresponding 3‐carbaldehydes 5a–d (the diformylated product 8 is isolated as a by‐product). A cyclizing Knoevenagel reaction of 5 with CH‐acidic nitriles 6 in the presence of piperidine gives substitu