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Regioselective synthesis of isopropenyl esters by ruthenium catalysed addition of N-protected amino-acids to propyne

โœ Scribed by Christophe Ruppin; Pierre H. Dixneuf; Serge Lecolier


Book ID
104217945
Publisher
Elsevier Science
Year
1988
Tongue
French
Weight
181 KB
Volume
29
Category
Article
ISSN
0040-4039

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The reaction of fluorinated 1,6- and 1,7-enynes, containing the moiety N(PG)C(CF(3))(CO(2)R), with diazo compounds in the presence of [RuCl(cod)(Cp\*)] (cod=cycloocta-1,5-diene, Cp\*=C(5)Me(5) , PG=protecting group) as the catalyst precursor leads to the formation of fluorinated 3-azabicyclo[3.1.0]h