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Regioselective synthesis of flavone derivatives via DMAP-catalyzed cyclization of o-alkynoylphenols

✍ Scribed by Masahito Yoshida; Yuta Fujino; Koya Saito; Takayuki Doi


Book ID
113928957
Publisher
Elsevier Science
Year
2011
Tongue
French
Weight
873 KB
Volume
67
Category
Article
ISSN
0040-4020

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Efficient preparations of anthracyclinones (1. and 21, the aglycones of the clinically important anthracycline antibiotics, daunorubicinl and adriamycin\* require a regiospecific synthesis of the tetracyclic skeleton with proper orientation of rings A and D substituents. One attractive route to 1 wo