✦ LIBER ✦
Regioselective synthesis of either α- or γ- amino acid derivatives via Li, Sn-masked, and/or Ge-masked dienolates
✍ Scribed by Yoshinori Yamamoto; Satoshi Hatsuya; Jun-ichi Yamada
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- French
- Weight
- 191 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
Either the a-(3) or y-amino acid derivatives (4) can be prepared with very high regioselectivity by treating diethyl azodicarboxylate (DEAD) with (i) lithium dienolates themselves (2) in certain cases, (ii) Sn-masked dienolates (5), or (iii) Ge-masked dienolates (6).