✦ LIBER ✦
Regioselective pyrrole synthesis from asymmetric β-diketone and conversion to sterically hindered porphyrin
✍ Scribed by Hiroshi Fujii; Tetsuhiko Yoshimura; Hitoshi Kamada
- Book ID
- 104256412
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- French
- Weight
- 208 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
The condensation of asymmetric I~-diketones with (x-oximinoacetoacetate esters affords pyrroles regioselectively. The mechanism of the regioselectivity is studied using ~C-NMR spectroscopy. Pyrrole having a neopentyl group at the 4-position is synthesized by the method, and further converted to a steric hindered porphyrin in good yield.