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Regioselective N9 alkylation of purine rings assisted by β-cyclodextrin

✍ Scribed by Qian Zhang; Gang Cheng; Yong-Zhen Huang; Gui-Rong Qu; Hong-Ying Niu; Hai-Ming Guo


Book ID
115542851
Publisher
Elsevier Science
Year
2012
Tongue
French
Weight
363 KB
Volume
68
Category
Article
ISSN
0040-4020

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## Abstract A highly selective method for the synthesis of N‐9 alkylated purine nucleoside derivatives __via__ an intermolecular hydrogen abstraction reaction between nitrogen radicals in purine rings and alkyl ethers was developed. Novel purine nucleoside derivatives were obtained with good to hig