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Regioselective N-acylation of arginine in oleum

✍ Scribed by Kravchenya, N. A.; Sokolov, K. N.; Sokolova, T. N.; Sokolov, N. K.


Book ID
118807916
Publisher
Springer
Year
2012
Tongue
English
Weight
76 KB
Volume
46
Category
Article
ISSN
0091-150X

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Agsslract. N-substituted pyrroles prepared from o-amino acids are converted to their mixed anhydrides by treatment with an acid chloride and base. Subsequent treatment with AlCls brings about rearrangement to the corresponding 2-acyl derivatives in overall yields of 55-S]%. The regioselectivity of