Regioselective green anomeric deacetylation catalyzed by lanthanide triflates

✍ Scribed by Anh Tuan Tran; Sophie Deydier; David Bonnaffé; Christine Le Narvor

• Book ID: 104095031
• Publisher: Elsevier Science
• Year: 2008
• Tongue: French
• Weight: 114 KB
• Volume: 49
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/j.tetlet.2008.01.106

✦ Synopsis

Lanthanide triflates, especially Nd(OTf) 3 , efficiently catalyze the regioselective transesterification of anomeric acetates. This method offers an efficient solution for the otherwise difficult removal of methyl uronates anomeric acetates as well as a green alternative to published protocols since the lanthanide catalysts are non-toxic and may be easily recycled and reused.