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Regioselective De Novo Synthesis of Cyanohydroxypyridines with a Concerted Cycloaddition Mechanism

✍ Scribed by Lu, Jin-Yong; Keith, John A.; Shen, Wei-Zheng; Schürmann, Markus; Preut, Hans; Jacob, Timo; Arndt, Hans-Dieter


Book ID
125471289
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
236 KB
Volume
130
Category
Article
ISSN
0002-7863

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✍ Hartnagel, Manfred ;Grimm, Klaus ;Mayr, Herbert 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 1002 KB

## Abstract Arenediazonium ions 1 undergo [2^+^ + 4] cycloadditions with (__E__)‐1,3‐pentadiene (2a), 2,3‐dimethylbutadiene (2b), and (__E__)‐2‐methyl‐1,3‐pentadiene (2c) to give dihydropyridazines or pyridazinium salts. While highly electrophilic diazonium ions and the unsymmetrical dienes 2a and