Regioselective control of the thiocarbonylation of terminal acetylenes with arylthiols catalyzed by Pd(II) and diphosphine ligands

✍ Scribed by B El Ali; J Tijani; A El-Ghanam; M Fettouhi

• Publisher: Elsevier Science
• Year: 2001
• Tongue: French
• Weight: 61 KB
• Volume: 42
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)02169-9

✦ Synopsis

Control of the regioselective thiocarbonylation of terminal acetylenes 1a-e with arylthiols 2a,b was successfully achieved by using Pd(OAc) 2 and 1,4-bis(diphenylphosphino)butane (dppb), or 1,3-bis(diphenylphosphino)propane (dppp), as catalysts. The formation of the thioesters 3 or 4 depends mainly on the type of ligand (dppp or dppb) and the solvent (THF or CH 2 Cl 2 ) under CO/H + or syngas mixture.