Regioselective addition ofnbutyllithium on secondary cinnamyl amides: “Michael" versus “contra-Michael" process

✍ Scribed by Nathalie Bremand; Ilan Marek; Jean F. Normant

• Book ID: 104261278
• Publisher: Elsevier Science
• Year: 1999
• Tongue: French
• Weight: 190 KB
• Volume: 40
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(99)00494-3

✦ Synopsis

Lithiated secondary cinnamyl amides undergo a preferred "eontra-Michael " addition of nbutyllithium, complexed with (-)sparteine, in a non polar solvent.