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Regioselective acylation at the 5- or 6-position of l-tryptophan derivatives

✍ Scribed by Yongwen Jiang; Dawei Ma


Book ID
104251890
Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
61 KB
Volume
43
Category
Article
ISSN
0040-4039

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✦ Synopsis


The reaction of 1-acyl tryptophan derivatives with chloroacetyl chloride or the reaction of 1-tosyl tryptophan derivatives with acetyl chloride provides the corresponding 6-acylation products, while acylation of the 3-oxo tryptophan derivative gives a 5-substituted product.


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