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Regioselective [2 + 2 + 2] Cycloaddition of a Nickel−Benzyne Complex with 1,3-Diynes

✍ Scribed by Deaton, Kimberly R.; Gin, Mary S.


Book ID
126773562
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
104 KB
Volume
5
Category
Article
ISSN
1523-7060

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✍ Ryan M. Stolley; Michael T. Maczka; Janis Louie 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 463 KB 👁 1 views

## Abstract A variety of bicyclic __N__,__N__‐disubstituted 2‐aminopyridines have been prepared from diynes and cyanamides by nickel‐catalyzed [2+2+2] cycloaddition reactions. The reactions proceeded at room temperature with low catalyst loading to afford 2‐aminopyridines in good to excellent yield