Regional over-representations on chromosomes 1q, 3q and 7q in the progression of hepatitis B virus-related hepatocellular carcinoma

Frequent rearrangements at minisatellite

Frequent rearrangements at minisatellite loci D1S7 (1p33-35), D7S22 (7q36-ter) and D12S11 (12q24.3-ter) in hepatitis B virus-positive hepatocellular carcinomas from Thai patients

✍ Catherine Kaplanski; Petcharin Srivatanakul; Christopher P. Wild 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 119 KB 👁 1 views

## Primary hepatocellular carcinoma (HCC) is one of the most common cancers in Thailand; chronic infection with hepatitis B virus (HBV) is endemic and represents a major risk factor for the development of this cancer. Several mechanisms for HBV-related hepatocarcinogenesis have been proposed, amon