✦ LIBER ✦

Regional intralymphatic infusion (ILI) of irradiated tumor cells with evidence of distant effects

✍ Scribed by Guy J. F. Juillard; Pamela J. J. Boyer; Charles H. Yamashiro; Harold D. Snow; Thomas H. Weisenburger; Timothy McCarthy; Robert J. Miller

Publisher: John Wiley and Sons
Year: 1977
Tongue: English
Weight: 420 KB
Volume: 39
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(197701)39:1<126::aid-cncr2820390122>3.0.co;2-5

No coin nor oath required. For personal study only.

✦ Synopsis

A case of canine lymphoma with radiographically-documented involvement of the para-aortic nodes is reported. Intralymphatic infusions (ILI) of cultured irradiate$ autochthonous tumor cells to remote lymph node bearing areas were associated with a dramatic initial shrinkage of the para-aortic lymphadenopathies. Three ILI timing schedules were used consecutively during a course of 10 treatments, allowing a comparison of responses in the same animal. The reported case suggests that a normal lymph node can be effectively "stimulated" by the same agent approximately every 3 weeks. A possible schedule for intralym phatic infusion is roposed for further investigation.

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