Regional histomorphology of cancellous bone in Macaca fascicularis

✍ Scribed by Edward W. Lipkin

• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: English
• Weight: 648 KB
• Volume: 39
• Category: Article
• ISSN: 0275-2565
• DOI: 10.1002/(sici)1098-2345(1996)39:3<179::aid-ajp3>3.0.co;2-w

✦ Synopsis

The structural and dynamic characteristics of cancellous bone from biopsy sites representing different degrees of weight bearing were quantified following double f luorochrome labeling of adult male Macaca fascicularis. A strong correlation of bone formation rate was found between the humerus, tibia, and iliac crest within the same individual. There was no significant correlation between differing biopsy sites for the structural measures of bone. The coefficient of variation for bone formation rate at different sites from the same animal was comparable to the coefficient of variation for different animals measured at the same biopsy site. The present study suggests that any accessible site of cancellous bone will yield a representative measure of bone formation rate, but that structural measures are not generalizable between different sites. o 1996 Wiley-Liss, Inc.