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Regional Distribution of Urocortin-like Immunoreactivity and Expression of Urocortin mRNA in the Human Brain

✍ Scribed by Kazuhiro Takahashi; Kazuhito Totsune; Masahiko Sone; Osamu Murakami; Fumitoshi Satoh; Zenei Arihara; Hironobu Sasano; Kazumi Iino; Toraichi Mouri


Book ID
117409168
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
337 KB
Volume
19
Category
Article
ISSN
0196-9781

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Distribution of urocortin-like immunorea
✍ Kozicz, TamοΏ½s; Yanaihara, Hitoshi; Arimura, Akira πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 647 KB

Urocortin was recently cloned from the rat midbrain. Urocortin is a member of the corticotropin releasing factor (CRF) peptide family and shows 45% sequence identity to CRF and 63% sequence identity to urotensin. It binds with a high affinity to CRF 1 and CRF 2 receptors, resulting in the stimulatio