Regional distribution of tyrosine, tryptophan, and their metabolites in the brain of epileptic El mice
โ Scribed by Shigeki Suzuki; Akitane Mori
- Publisher
- Springer
- Year
- 1992
- Tongue
- English
- Weight
- 516 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0364-3190
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Repeated administration of diazepam leads to remarkable accumulation of N-desmethyldiazepam in white matter structures and in subcortical areas such as thalamus, hypothalamus, and hypophysis. Diazepam and the hydroxylated metabolites were present in lesser amounts. The distribution pattern of diazep