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Regional chromosomal localisation of APOA2 to 1q21–1q23

✍ Scribed by H. R. Middleton-Price; J. A. Berghe; J. Scott; T. J. Knott; S. Malcolm


Publisher
Springer
Year
1988
Tongue
English
Weight
336 KB
Volume
79
Category
Article
ISSN
0340-6717

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✦ Synopsis


Using in situ hybridisation, we have mapped APOA2 to the 1q21-1q23 region of chromosome 1. DNA hybridisation to somatic cell hybrids made from cells carrying a balanced translocation between X and 1 confirms the localisation as proximal to 1q23. This was further confirmed by the presence of two polymorphic alleles in a cell line carrying a deletion of 1q25-1q32.


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