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Regional cerebral energy metabolism in bicuculline induced seizures

✍ Scribed by Suzanne Dworsky; David W. McCandless


Publisher
Springer
Year
1987
Tongue
English
Weight
357 KB
Volume
12
Category
Article
ISSN
0364-3190

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## Abstract Isoniazid is a useful chemical convulsant in that metabolic events associated with the preseizure state can be easily examined. In the present study, net levels of glucose, glycogen, ATP, and phosphocreatine were measured using enzymatic techniques in control mice, and in those injected

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## Abstract To evaluate the effects of substrate deficiency on cerebral function, metabolism, and blood flow during seizures, rats were injected intravenously with bicuculline (1.2 mg Β· kg^βˆ’1^) following a 24‐hour period of starvation. During the course of seizures, blood glucose concentrations fel