Regional cerebral blood flow changes following chronic administration of antidepressant drugs
β Scribed by Stefano Passero; Marcello Nardini; Noe' Battistini
- Book ID
- 116120205
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 755 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0278-5846
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π SIMILAR VOLUMES
## Abstract ## Objective Reversible/irreversible abnormalities of regional cerebral blood flow (rCBF) are seen in patients with depression. However, in lateβlife depression there is little evidence of a longitudinal change in rCBF through remission. We examined whether the decreased rCBF in indivi
H-labeled physostigmine (50 pg. kg-') was administered intravenously to rats, and its concentration in brain tissue and spinal cord was assessed by quantitative autoradiography. Regional cerebral blood flow (rCBF) was measured with i~do-'~C-antipyrine autoradiography in control rats and in animals i