Regional brain GABA metabolism and release during hepatic coma produced in rats chronically treated with carbon tetrachloride

Glutamate decarboxylase inhibition and v

Glutamate decarboxylase inhibition and vitamin B6 metabolism in brain of cirrhotic rats chronically treated with carbon tetrachloride

✍ M. Díaaz-Muñtoz; Ricardo Tapia 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 672 KB

In a previous work we found that the activity of glutamate decarboxylase (GAD), the enzyme responsible for the synthesis of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), is decreased in comatose cirrhotic rats after chronic treatment with CCl4. In the present report we studied the