Region-specific effects of chronic lithium administration on neuropeptide Y and somatostatin mRNA expression in the rat brain
✍ Scribed by Olof Zachrisson; Aleksander A. Mathé; Carina Stenfors; Nils Lindeforsa
- Book ID
- 118406933
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 346 KB
- Volume
- 194
- Category
- Article
- ISSN
- 0304-3940
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## Abstract Lithium is known to exert its biochemical action on cells and tissues by inhibiting the enzymic conversion of inositol monophosphates to inositol. However, it is not clear whether this inhibitory action may lead to changes in the de novo biosynthesis of phosphatidylinositol and its phos
The effects of lithium on brain regional concentrations of substance P (SP)-, neurokinin A (NKA)-, calcitonin gene-related peptide (CGRP)-and neuropeptide Y (NPY)-like immunoreactivities (-LI) were studied in rat. In the pilot study, rats were divided into three groups that were administered vehicle