๐”– Bobbio Scriptorium
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Region- and cell type-specific de novo DNA methylation in cultured mammalian cells

โœ Scribed by Mitchell S. Turker; Padmaja Mummaneni; Peggy L. Bishop

Book ID
112501188
Publisher
Springer
Year
1991
Tongue
English
Weight
996 KB
Volume
17
Category
Article
ISSN
1572-9931

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## Abstract Epigenetic remodeling is a hallmark of cancer, with the frequent acquisition of de novo DNA methylation in CpG islands. However, the functional relevance of de novo DNA methylation in cancer is less well defined. To begin to address this issue in Bโ€cells, we used BeadArray assays to sur