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Regiocontrolled dieckmann condensation of 3,4-Bis(methoxycarbonylmethyl) levoglucosenone derivative

✍ Scribed by Iskakova, M. M.; Biktagirov, I. M.; Faizullina, L. Kh.; Salikhov, Sh. M.; Safarov, M. G.; Valeev, F. A.


Book ID
121552891
Publisher
SP MAIK Nauka/Interperiodica
Year
2014
Tongue
English
Weight
218 KB
Volume
50
Category
Article
ISSN
1070-4280

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✍ Dr. S. M. Abdel-Wahhab (Mrs.); Dr. N. R. El-Rayyes 📂 Article 📅 1971 🏛 John Wiley and Sons 🌐 English ⚖ 360 KB

## Abstract The condensation of 5‐methyl‐thiophen‐2‐aldehyde with dimethyl succinate in the presence of potassium t‐butoxide or sodium hydride gave predominantly (E)‐3‐methoxy‐carbonyl‐4‐(5′‐methyl‐2′‐thienyl)‐but‐3‐enoic acid **1a**, whose configuration is proved by cyclisation with sodium acetate