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Regio-specific hydroxylation of isoflavonoids using bacterial cytochrome P450s

โœ Scribed by Byung-gee Kim; Kwon-young Choi; Nahum Lee; Bishnu Prasad Pandey


Book ID
113683025
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
79 KB
Volume
108
Category
Article
ISSN
1389-1723

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Preparation of human metabolites of prop
โœ Christopher R. Otey; Geethani Bandara; James Lalonde; Katsuyuki Takahashi; Franc ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 140 KB

## Abstract Testing the toxicities and biological activities of the human metabolites of drugs is important for development of safe and effective pharmaceuticals. Producing these metabolites using human cytochrome P450s is difficult, however, because the human enzymes are costly, poorly stable, and