Regio- and stereoselectivity of the formation of 1,3-oxazolidines in the reaction of l-ephedrine with phenylglyoxal. Unexpected rearrangement of 2-benzoyl-3,4-dimethyl-5-phenyl-1,3-oxazolidine to 4,5-dimethyl-3,6-diphenylmorpholin-2-one.
β Scribed by Felix Polyak; Tatiana Dorofeeva; Gunars Zelchans; Gennady Shustov
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- French
- Weight
- 203 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
## Molecular complexes of an oxazolidine prodrug of (-)-ephedrine, cis-2-(4-methoxyphenyl)-3,4-dimethyl- 5-phenyloxazolidine, with Ξ±-, Ξ²-, dimethyl-Ξ²-(DM-Ξ²-) and hydroxypropl-Ξ²-(HP-Ξ²-) cyclodextrins (CDs) were examined using ionspray mass spectrometry. The results suggest, under our experimental c
Formation and Reaction of 2-Metalated N-Boc-4,4-dimethyl-1,3oxazolidines in the Presence of (-)-Sparteine: New Chiral Formyl Anion Equivalents. -The reaction proceeds with good enantioselectivity and in the presence of MgBr 2 also with good diastereoselectivity. -(KISE,