## Abstract The reaction of the tetraaminopyrimidine 1 with the chalcones **2a‐f** yields, in the presence of catalytic amounts of acetic acid, the 1__H__‐pyrimido[4,5‐__b__][1,4]diazepine derivatives **3a‐f.** The cyclization process consists of a condensation reaction and a Michael type addition.
Regio- and Stereochemical Features of the Reactions of 1,2,5-Trimethylpiperidin-4-one with Chalcone.
✍ Scribed by S. Z. Vatsadze; M. L. Kostochka; V. P. Lezina; V. G. Vinokurov; N. V. Zyk
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 18 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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## Abstract 1,2,4‐Triazin‐5(2__H__)‐ones 1 react as well with phenols, resorinol and its dimethyl ethers, as with dimethyland diethylaniline, yielding 6‐aryl‐1,6‐didydro‐1,2,4‐triazin‐5(2__H__)‐ones 2, 4–8, 12–15. Oxidation of the 1,6‐dihydroadducts 2a,b gives the corresponding 3‐aryl‐6‐hydroxyphen