InTech, 2013. โ 853 p. โ ISBN 9535111085; 9789535111085.
This book fairly reflects the state of the art of disciplines at this time as well as their therapeutic application. It covers numerous topics, such as stem cells, cell culture, polymer synthesis, novel biomaterials, drug delivery, therapeutics, and the creation of tissues and organs. The goal is to have this book serve as a reference for graduate students, post-docs, teachers, scientists and physicians, and as an explanatory analysis for executives in biotech and pharmaceutical companies.
The fundamental concept of Tissue Engineering and Regenerative Medicine is appealing to scientists, physicians, and lay people alike: to heal tissue or organ defects that the current medical practice deems difficult or impossible to cure.
Tissue engineering combines cells, engineering, and materials methods with suitable biochemical and physiochemical factors to improve or replace biologic functions.
Regenerative medicine is a new branch of medicine that attempts to change the course of chronic disease, in many instances regenerating failing organ systems lost due to age, disease, damage, or congenital defects.
Contents:Preface.
Stem Cells in Regenerative Medicine.
Placenta-Derived Stem Cells as a Source for Treatment of Lung and Liver Disease in Cystic Fibrosis.
Isolation of Bone Marrow Stromal Cells: Cellular Composition is Technique-Dependent.
The ASC: Critical Participants in Paracrine-Mediated Tissue Health and Function.
Dental-Related Stem Cells and Their Potential in Regenerative Medicine.
Induce Differentiation of Embryonic Stem Cells by Co-Culture System.
Oral and Maxillofacial Tissue Engineering with Adipose-Derived Stem Cells.
Is the Articular Cartilage Regeneration Approachable Through Mesenchymal Stem Cells Therapies?
Adipose Derived Stem Cells: Current State of the Art and Prospective Role in Regenerative Medicine and Tissue Engineering.
Regulatory Issues in the Therapeutic Use of Stem Cells.
Scaffolds and Matrices.
The Evolution of Three-Dimensional Cell Cultures Towards Unimpeded Regenerative Medicine and Tissue Engineering.
Naturally Derived Biomaterials: Preparation and Application.
Biomaterials for Cardiac Tissue Engineering.
Treatment of Bone Defects โAllogenic Platelet Gel and Autologous Bone Technique.
Skeletal Muscle Ventricles (SMVs) and Biomechanical Hearts (BMHs) with a Self-Endothelializing Titanized Blood Contacting Surface.
Cartilage Tissue Engineering: The Role of Extracellular Matrix (ECM) and Novel Strategies.
Fabrication of PGA/PLA Scaffold with the Shape of Human Nose.
Regeneration of Tissues and Organs.
Bone Marrow-Derived Cells Regenerate Structural and Functional Lower Urinary Tracts.
Corneal Endothelial Tissue Bioengineering Using Cultured Human Corneal Endothelial Precursor Cells.
Angiogenesis โ The Key to Regeneration.
Engineering of Inflammation-Resistant Osteochondral Cells.
Tissue Engineered Animal Sparing Models for the Study of Joint and Muscle Diseases.
Importance of Extracellular Environment for Regenerative Medicine and Tissue Engineering of Cartilagious Tissue.
Potential of Different Tissue Engineering Strategies in the Bladder Reconstruction.
Advances in Bone Tissue Engineering.
Bone Engineering: A Matter of Cells, Growth Factors and Biomaterials.
Adaptation and Evolution in a Gravitational Environment โA Theoretical Framework for the Limited Re-Generative Post-Natal Time Window of the Heart in Higher Vertebrates.
Skeletal Muscle Regeneration for Clinical Application.
Delivery Systems and Role of Growth Factors for Alveolar Bone Regeneration in Dentistry.
Clinical Perspective of Tissue Engineering and Cell-Based Therapies.
Regenerative Medicine for Neurological Diseases with the Use of Electrical Stimulation.
Pigmented Skin Models: Understand the Mechanisms of Melanocytes.
Cell Therapy and Muscle Regeneration: Skeletal Myogenic Differentiation of Urine-Derived Stem Cells for Potential Use in Treatment of Urinary Incontinence.
Autologous Muscular Treatment Options for Endstage Heart Failure โA Critical Appraisal of the Dynamic Cardiomyoplasty (DCMP) vs. a New Concept of a Closed-Loop Controlled DCMP (CLC-DCMP).
Complications of Post-Transplant Immunosuppression.