Regeneration of nigrostiatal dopaminergic axons by transplantation of olfactory ensheathing cells is accompanied by elimination of the fibrotic scar formation in the lesion site

Regeneration of nigrostriatal dopaminerg

Regeneration of nigrostriatal dopaminergic axons after transplantation of olfactory ensheathing cells and fibroblasts prevents fibrotic scar formation at the lesion site

✍ Xichuan Teng; Isao Nagata; Hong-Peng Li; Junko Kimura-Kuroda; Kazunori Sango; Ko 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 540 KB

## Abstract The fibrotic scar formed after central nervous system injury has been considered an obstacle to axonal regeneration. The present study was designed to examine whether cell transplantation into a damaged central nervous system can reduce fibrotic scar formation and promote axonal regener