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Regarding exchange of the 2-hydrogen of thiamine through the tetrahedral intermediate formed by nucleophilic addition

โœ Scribed by Paul Haake


Book ID
104234125
Publisher
Elsevier Science
Year
1981
Tongue
French
Weight
138 KB
Volume
22
Category
Article
ISSN
0040-4039

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โœฆ Synopsis


Kinetic data demonstrates that the exchange of hydrogen at the 2-position of thiazolium ions cannot occur through the tetrahedral intermediate formed by nucleophilic addition of hydroxide to the 2-position.


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A series of guanidiniocarbonyl pyrrole receptors has been synthesized which bind carboxylates by ion pairing in combination with multiple hydrogen bonds. Their binding properties with various carboxylates have been investigated using NMR titration studies in 40 % water/DMSO (v/v). The best receptor