## Abstract ## BACKGROUND: Esophageal atresia with or without tracheoesophageal fistula (EA/TEF) and congenital diaphragmatic hernia (CDH) are severe congenital anomalies. Their etiologies are mostly unknown and are thought to be multifactorial. No specific environmental factors have consistently
Regarding environmental factors in the etiology of esophageal atresia and congenital diaphragmatic hernia
β Scribed by Silvia Ceccanti; Denis A. Cozzi; Mauro Ceccanti
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 37 KB
- Volume
- 82
- Category
- Article
- ISSN
- 1542-0752
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
BACKGROUND: Two severe birth defects, congenital diaphragmatic hernia (CDH) and esophageal atresia (EA) with or without tracheoesophageal fistula (TEF), have traditionally been analyzed separately in epidemiological studies. Lung hypoplasia (LH), part of the CDH spectrum, is not usually associated w
## Abstract Esophageal atresia and/or tracheoesophageal fistula (EA/TEF) are severe congenital anomalies. Although recent years have brought significant improvement in clinical treatment, our understanding of the etiology of these defects is lagging. Many genes and genetic pathways have been implic
In this review, we discuss recent advances in the study of the pathogenesis of congenital diaphragmatic hernia (CDH). Much of the research has involved the use of an animal model of CDH in which diaphragmatic defects are produced in fetal rats by administering the herbicide nitrofen to dams during m