𝔖 Bobbio Scriptorium
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REGARDING CYP450 2D6 POOR METABOLIZERS

✍ Scribed by Harry Ahdieh

Book ID
109137519
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
35 KB
Volume
8
Category
Article
ISSN
1530-7085

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πŸ“œ SIMILAR VOLUMES

No evidence of increased adverse drug re
No evidence of increased adverse drug reactions in cytochrome P450 CYP2D6 poor metabolizers treated with fluoxetine or nortriptyline
✍ Rebecca L. Roberts; Roger T. Mulder; Peter R. Joyce; Suzanne E. Luty; Martin A. πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 75 KB

## Abstract The polymorphic enzyme cytochrome P450 CYP2D6 is involved in the metabolism of many antidepressants, including nortriptyline and fluoxetine. Some 7%–10% Caucasians have inactivating mutations in both alleles of the __CYP2D6__ gene, and are referred to as poor metabolizers (PMs). Several