Refractory post-pancreatitis thrombotic thrombocytopenic purpura: response to rituximab
โ Scribed by Jimmy Ruiz; Prasad R. Koduri; Manuel Valdivieso; Prabodh C. Shah
- Book ID
- 105988528
- Publisher
- Springer
- Year
- 2004
- Tongue
- English
- Weight
- 104 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0939-5555
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๐ SIMILAR VOLUMES
## Abstract Plasma exchange is the standard treatment for thrombotic thrombocytopenic purpura (TTP). For patients refractory to plasma exchange, treatment options are limited and often unsuccessful. The platelet thrombi that form in acquired TTP are believed to result from the presence of procoagul
Three patients (one with idiopathic thrombocytopenic purpura [ITP] and two with thrombotic thrombocytopenic purpura [TTP]) were treated with rituximab (anti-CD20 chimeric antibody) at a dose of 325 mg/m 2 administered weekly after they failed standard therapies. The patient with ITP who did not resp