Refractory generalized seizures and cerebellar ataxia associated with anti-GAD antibodies responsive to immunosuppressive treatment

Response to steroid treatment in anti–gl

Response to steroid treatment in anti–glutamic acid decarboxylase antibody-associated cerebellar ataxia, stiff person syndrome and polyendocrinopathy

✍ Ji-Youn Kim; Eun Joo Chung; Jong-Hun Kim; Ki-Young Jung; Won Yong Lee 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 60 KB

Glutamic acid decarboxylase (GAD) is an enzyme that catalyzes the conversion of glutamate to ␥-aminobutyric acid (GABA). Anti-GAD antibody (GAD-Ab) is considered to be a marker for stiff person syndrome (SPS), 1 insulin-dependent diabetes mellitus (IDDM), and polyendocrine autoimmune syndrome. 2 Add