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Refinement of the solution structure of the heparin-binding domain of vascular endothelial growth factor using residual dipolar couplings

โœ Scribed by Melissa E. Stauffer; Nicholas J. Skelton; Wayne J. Fairbrother


Book ID
110336063
Publisher
Springer Netherlands
Year
2002
Tongue
English
Weight
110 KB
Volume
23
Category
Article
ISSN
0925-2738

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Vascular endothelial growth factor (VEGF) is a potent angiogenic factor with a unique specificity for vascular endothelial cells. In addition to its role in vasculogenesis and embryonic angiogenesis, VEGF is implicated in pathologic neovascularization associated with tumors and diabetic retinopathy.