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Refinement of the RP17 locus for autosomal dominant retinitis pigmentosa, construction of a YAC contig and investigation of the candidate gene retinal fascin

✍ Scribed by Bardien-Kruger, Soraya; Greenberg, Jacquie; Tubb, Benjamin; Bryan, Joseph; Queimado, Lurdes; Lovett, Michael; Ramesar, Rajkumar S


Book ID
110024809
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
154 KB
Volume
7
Category
Article
ISSN
1018-4813

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No evidence of linkage between the locus
✍ Jacqueline B. JimΓ©nez; Christine Samanns; Anke Watty; Johann Pongratz; Jane E. O πŸ“‚ Article πŸ“… 1991 πŸ› Springer 🌐 English βš– 224 KB

A linkage analysis has been performed on three Australian families segregating for autosomal dominant retinitis pigmentosa (ADRP). No evidence of linkage has been found in any of the pedigrees studied between the locus D3S47 and the gene for ADRP. The D3S47 locus was found to show very close linkage