The build-up procedure for predicting low-energy conformations of polypeptides has been extended to cover the case of peptides in aqueous solutions. The revised procedure consists of five steps to be applied to each stage of the build-up. I. All low-energy minima of each of the two fragments to be j
โฆ LIBER โฆ
Refinement of protein conformations using a macromolecular energy minimization procedure
โ Scribed by Levitt, Michael; Lifson, Shneior
- Book ID
- 120163489
- Publisher
- Elsevier Science
- Year
- 1969
- Tongue
- English
- Weight
- 667 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0022-2836
No coin nor oath required. For personal study only.
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The major macromolecular crystallographic refinement packages restrain models to ideal geometry targets defined as single values that are independent of molecular conformation. However, ultrahigh-resolution X-ray models of proteins are not consistent with this concept of ideality and have been used
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