Refinement and Quality Assessment of Predicted Protein Structures
โ Scribed by Zhang, Jiong; Zhang, Jingfen; Xu, Dong; Shang, Yi; Kosztin, Ioan
- Book ID
- 123049919
- Publisher
- Biophysical Society
- Year
- 2012
- Tongue
- English
- Weight
- 36 KB
- Volume
- 102
- Category
- Article
- ISSN
- 0006-3495
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The growing flood of new experimental data generated by genome sequencing has provided an impetus for the development of automated methods for predicting the functions of proteins that have been deduced by sequence analysis and lack experimental characterization. Prediction of Protein Structures, F
## Abstract We present a novel method called RosettaHoles for visual and quantitative assessment of underpacking in the protein core. RosettaHoles generates a set of spherical cavity balls that fill the empty volume between atoms in the protein interior. For visualization, the cavity balls are aggr