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Reference intervals of CD3, CD4, CD8, CD4/CD8, and absolute CD4 values in asian and non-asian populations

✍ Scribed by Raylee R. Howard; Cynthia S. Fasano; Linda Frey; Claramae H. Miller

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 215 KB
Volume: 26
Category: Article
ISSN: 0196-4763
DOI: 10.1002/(sici)1097-0320(19960915)26:3<231::aid-cyto9>3.0.co;2-h

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✦ Synopsis

A study to determine reference intervals in normal Asian and non-Asian populations for CD3 (T cells), CD4 (T helperlinducer cells), CD8 (T suppressor/cytotoxic cells), and for the CD4/CD8 ratio and absolute CD4 lymphocyte count was performed. Coulter Clone/Cytostat reagents were used. The samples were lysed using the Coulter Q-Prep and analyzed on the Coulter Profile II flow cytometer. The Asian population appeared to have a lower mean percentage of CD3 and CD4 cells, a lower CD4/CD8 ratio, and lower absolute CD4 lymphocytes. These findings indicate that race should be a consideration in determining reference intervals for immunophenotyping for CD3, CD4, and CD8. o 1996 Wiley-Liss, Inc.

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