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Reexamining interaction of the SH2 domains of SYP and GAP with insulin and IGF-1 receptors in the two-hybrid system

✍ Scribed by Betty Lamothe; Danielle Bucchini; Jacques Jami; Rajiv L. Joshi


Book ID
117521894
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
397 KB
Volume
182
Category
Article
ISSN
0378-1119

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Classical insulin and IGF-1 receptors are azP2 heterotetrameric complexes synthesized from two identical a0 half-receptor precursors [I ,21. Recent data strongly suggests, however, that nonidentical ap half-receptor precursors can assemble to generate hybrid holoreceptor species both in vivo and in