Reevaluation of rebound regression in disseminated carcinoma of the breast

✍ Scribed by Laurence H. Baker; Vainutis K. Vaitkevicius

• Publisher: John Wiley and Sons
• Year: 1972
• Tongue: English
• Weight: 329 KB
• Volume: 29
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/1097-0142(197205)29:5<1268::aid-cncr2820290521>3.0.co;2-o

✦ Synopsis

In patients with disseminated carcinoma of the breast on estrogen therapy that develop progression of their disease, sudden cessation of estrogen was found to produce tumor regression. I n a study of 97 patients with breast carcinoma treated with estrogen and followed closely, 25 patients had a trial of sudden hormonal withdrawal because of progression of their disease. Of these, eight patients (32%) had tumor remission lasting from 3 to 10 months * Fellow in Oncology.