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Reductive elimination pathway for homocysteine to methionine conversion in cobalamin-dependent methionine synthase

✍ Scribed by Pawel M. Kozlowski; Takashi Kamachi; Manoj Kumar; Kazunari Yoshizawa


Book ID
111877384
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
844 KB
Volume
17
Category
Article
ISSN
1432-1327

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The reaction of cobaloxime(I) with diverse quatemary ammonium salts Icads, in general, to a group transfer from ainogen to cobalt. The behaviour of the salts in these transalkylation~ is consistent with an SN~ mechanism. involving Co(l) as a nucleophile. In a model study of the cobdamin-dependent me