Reductive defluorination of polyfluoroarenes by zinc in aqueous ammonia

✍ Scribed by Sergey S. Laev; Vitalij D. Shteingarts

• Book ID: 104257092
• Publisher: Elsevier Science
• Year: 1997
• Tongue: French
• Weight: 209 KB
• Volume: 38
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(97)00730-2

✦ Synopsis

Aqueous ammonia has been found to be a good and versatile medium for the reductive defluorination of polyfluoroarenes by zinc. Upon the reduction of pentefluombenmic acid, 2,3,4,5,6pentafluorobenzyl alcohol, pentafluoropyridine and helXatluoro-2-naphthoic acid individual products derived from the removal of one fluorine atom have been obtained.