Reductive coupling of carbonyl compounds using lanthanum metal

✍ Scribed by Toshiki Nishino; Yutaka Nishiyama; Noboru Sonoda

• Publisher: John Wiley and Sons
• Year: 2000
• Tongue: English
• Weight: 157 KB
• Volume: 11
• Category: Article
• ISSN: 1042-7163
• DOI: 10.1002/(sici)1098-1071(2000)11:1<81::aid-hc12>3.0.co;2-1

✦ Synopsis

We found that lanthanum metal was an excellent agent for the reduction of carbonyl compounds in the presence of a catalytic amount of iodine. When carbonyl compounds were treated with lanthanum metal in the presence of a catalytic amount of iodine, the reductive coupling of the carbonyl compounds proceeded efficiently to afford the corresponding vic-diols in moderate to good yields.