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Reduction of β-amyloid-induced neurotoxicity on hippocampal cell cultures by moderate acidosis is mediated by transforming growth factor β

✍ Scribed by R. Uribe-San Martín; R. Herrera-Molina; L. Olavarría; G. Ramírez; R. von Bernhardi


Book ID
116788807
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
541 KB
Volume
158
Category
Article
ISSN
0306-4522

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Vitamin D and retinoids cooperate to inhibit the proliferation and induce the differentiation of human myelomonocytic U937 leukemia cells. In the present work, we investigated the role of TGF-␤ as an endogenous mediator of this process. We found that the TGF-␤1 precursor began to accumulate in cell